STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62150.1Transcriptional regulator, GntR family with LacI sensor; PFAM: Bacterial regulatory proteins, gntR family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000524:IPR001761; KEGG: sta:STHERM_c18490 transcriptional repressor; PFAM: HTH transcriptional regulator, GntR; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family with LacI sensor. (371 aa)    
Predicted Functional Partners:
AEJ61317.1
PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c10200 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family.
  
     0.772
AEJ62356.1
PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843; KEGG: sta:STHERM_c20570 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family.
  
     0.721
AEJ61321.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit.
    
 
 0.712
AEJ62148.1
PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR010182; KEGG: sta:STHERM_c18470 hypothetical protein; PFAM: Peptidase M20; Peptidase M20, dimerisation; SPTR: Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; TIGRFAM: Acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase.
  
    0.671
AEJ62149.1
PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: uncharacterized protein, YigZ family; COGs: COG1739 conserved hypothetical protein; InterPro IPR001498:IPR015269:IPR015796; KEGG: sta:STHERM_c18480 hypothetical protein; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; Uncharacterised protein family UPF0029, Impact, C-terminal; SPTR: Uncharacterized protein family UPF0029, Impact; TIGRFAM: Uncharacterised protein family UPF0029, Impact.
       0.651
AEJ62151.1
PFAM: Glycosyl hydrolases family 43; COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: sta:STHERM_c18500 beta-xylosidase; PFAM: Glycoside hydrolase, family 43; SPTR: Xylan 1,4-beta-xylosidase.
     
 0.608
AEJ62153.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c18520 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.
       0.605
AEJ62152.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c18510 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.
       0.604
AEJ62154.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c18530 multiple sugar binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1.
       0.470
AEJ62498.1
Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein.
   
 
 0.467
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (24%) [HD]