Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62162.1PSP1 domain protein; PFAM: PSP1 C-terminal conserved region; COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: sta:STHERM_c18600 hypothetical protein; PFAM: PSP1, C-terminal; SPTR: PSP1 domain protein. (307 aa)    
Predicted Functional Partners:
AEJ62163.1
PFAM: Protein of unknown function (DUF327); COGs: COG1728 conserved hypothetical protein; InterPro IPR005585; KEGG: sta:STHERM_c18610 hypothetical protein; PFAM: Protein of unknown function DUF327; SPTR: Putative uncharacterized protein.
  
  
 0.802
AEJ62164.1
PFAM: Protein of unknown function, DUF583; COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: sta:STHERM_c18620 hypothetical protein; PFAM: Protein of unknown function DUF583; SPTR: Putative uncharacterized protein.
     
 0.764
AEJ62165.1
PFAM: Peptidase family M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: sta:STHERM_c18630 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; SPTR: Peptidase M23.
       0.758
rny
2,3 cyclic-nucleotide 2-phosphodiesterase; Endoribonuclease that initiates mRNA decay.
 
  
 0.743
AEJ61208.1
PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sta:STHERM_c09090 flagellar hook-basal body complex protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: Flagellar hook-basal body complex protein FliE.
   
   0.647
AEJ61216.1
PFAM: Flagellar hook capping protein; COGs: COG1843 Flagellar hook capping protein; InterPro IPR005648; KEGG: sta:STHERM_c09170 flagellar hook assembly protein; PFAM: Flagellar hook capping protein; SPTR: Flagellar hook capping protein.
    
   0.640
AEJ61657.1
Flagellin domain protein; Component of the core of the flagella. Belongs to the bacterial flagellin family.
    
 
 0.640
AEJ62490.1
MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: sta:STHERM_c21890 chemotaxis protein methyltransferase; PFAM: MCP methyltransferase, CheR-type; SMART: MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase, CheR-type.
    
   0.640
AEJ62161.1
KEGG: sta:STHERM_c18590 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.596
AEJ62368.1
Dihydroorotate dehydrogenase electron transfer subunit; PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: sta:STHERM_c20590 oxidoreductase FAD/NAD(P)-binding domain-containing protein; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding [...]
 
  
 0.535
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.