STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62163.1PFAM: Protein of unknown function (DUF327); COGs: COG1728 conserved hypothetical protein; InterPro IPR005585; KEGG: sta:STHERM_c18610 hypothetical protein; PFAM: Protein of unknown function DUF327; SPTR: Putative uncharacterized protein. (166 aa)    
Predicted Functional Partners:
AEJ62164.1
PFAM: Protein of unknown function, DUF583; COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: sta:STHERM_c18620 hypothetical protein; PFAM: Protein of unknown function DUF583; SPTR: Putative uncharacterized protein.
     
 0.815
AEJ62162.1
PSP1 domain protein; PFAM: PSP1 C-terminal conserved region; COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: sta:STHERM_c18600 hypothetical protein; PFAM: PSP1, C-terminal; SPTR: PSP1 domain protein.
  
  
 0.809
AEJ62165.1
PFAM: Peptidase family M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: sta:STHERM_c18630 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; SPTR: Peptidase M23.
       0.807
AEJ62161.1
KEGG: sta:STHERM_c18590 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.556
AEJ62166.1
Hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR001130:IPR015991; KEGG: sta:STHERM_c18640 hypothetical protein; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote.
       0.553
AEJ62167.1
TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.531
AEJ61234.1
PFAM: Protein of unknown function (DUF342); COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: sta:STHERM_c09350 polymerase most proteins contain PALM domain HD hydrolase domain and Zn-ribbon domain; PFAM: Protein of unknown function DUF342; SPTR: Putative uncharacterized protein.
  
     0.514
AEJ60323.1
PFAM: Protein of unknown function (DUF342); COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: sta:STHERM_c00360 polymerase most proteins contain PALM domain HD hydrolase domain and Zn-ribbon domain; PFAM: Protein of unknown function DUF342; SPTR: Putative uncharacterized protein.
  
     0.489
fliW
Flagellar assembly factor fliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
     0.473
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
       0.440
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.