STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62175.11-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; PFAM: AIR carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: sta:STHERM_c18730 hypothetical protein; PFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase. (249 aa)    
Predicted Functional Partners:
AEJ62176.1
Conserved hypothetical protein CHP00268; PFAM: NAD synthase; TIGRFAM: TIGR00268 family protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR001962:IPR005232; KEGG: sta:STHERM_c18740 hypothetical protein; PFAM: Asparagine synthase; SPTR: Asparagine synthase; TIGRFAM: Conserved hypothetical protein CHP00268.
 
 
 0.993
AEJ62177.1
PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; COGs: COG1641 conserved hypothetical protein; HAMAP: UPF0272 protein; InterPro IPR002822; KEGG: dma:DMR_16560 hypothetical protein; PFAM: Protein of unknown function DUF111; SPTR: Putative uncharacterized protein; TIGRFAM: Protein of unknown function DUF111; Belongs to the LarC family.
 
  
 0.978
AEJ60665.1
PFAM: Uncharacterized conserved protein (DUF2088); COGs: COG3875 conserved hypothetical protein; KEGG: sta:STHERM_c04160 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.772
AEJ61743.1
Cobalamin (vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: sta:STHERM_c13440 hypothetical protein; PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein.
 
    0.764
AEJ62178.1
Diverse 7TM receptor transmembrane region; PFAM: 7TM diverse intracellular signalling; InterPro IPR011623; KEGG: sta:STHERM_c18750 hypothetical protein; PFAM: Diverse 7TM receptor, transmembrane region; SPTR: Diverse 7TM receptor transmembrane region.
       0.558
AEJ61866.1
PFAM: Domain of unknown function (DUF362); COGs: COG2006 conserved hypothetical protein; InterPro IPR007160:IPR001450; KEGG: sta:STHERM_c15570 iron-sulfur cluster-binding protein; PFAM: Protein of unknown function DUF362; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Putative uncharacterized protein.
 
     0.516
AEJ62174.1
HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834:IPR006439; KEGG: sta:STHERM_c18720 hydrolase of the HAD superfamily; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1.
       0.509
AEJ62173.1
KEGG: sta:STHERM_c18710 cytoskeletal protein; SPTR: Putative uncharacterized protein.
       0.479
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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