STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62181.1Protein of unknown function DUF114; PFAM: Serine dehydrogenase proteinase; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR002825; KEGG: sta:STHERM_c18780 periplasmic serine protease; PFAM: Protein of unknown function DUF114; SPTR: Putative uncharacterized protein. (284 aa)    
Predicted Functional Partners:
AEJ62182.1
PFAM: Rhomboid family; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: sta:STHERM_c18790 rhomboid family protein; PFAM: Peptidase S54, rhomboid; SPTR: Rhomboid family protein.
 
  
 0.745
trpB-2
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.528
AEJ62180.1
PFAM: Trp repressor protein; TIGRFAM: trp operon repressor, proteobacterial; InterPro IPR000831; KEGG: sta:STHERM_c18770 hypothetical protein; PFAM: Trp repressor; SPTR: Putative uncharacterized protein.
       0.528
AEJ62183.1
Iron sulfur domain-containing, CDGSH-type; PFAM: Iron-binding zinc finger CDGSH type; InterPro IPR018967:IPR006622; KEGG: sta:STHERM_c18800 zinc finger, CDGSH-type; PFAM: Iron sulphur domain-containing, CDGSH-type; SPTR: Iron sulfur-containing domain, CDGSH-type.
       0.438
trpF
PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate (PRA) isomerase; COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR001240; KEGG: sta:STHERM_c01830 anthranilate synthase component; PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate isomerase (PRAI); SPTR: Indole-3-glycerol phosphate synthase; Belongs to the TrpF family.
     
 0.412
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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