STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62188.1PFAM: Ferric uptake regulator family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: fnu:FN2045 ferric uptake regulation protein; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; Belongs to the Fur family. (145 aa)    
Predicted Functional Partners:
AEJ62544.1
Regulatory protein ArsR; PFAM: Transcriptional regulator PadR-like family; InterPro IPR001845; KEGG: sta:STHERM_c22490 hypothetical protein; SMART: HTH transcriptional regulator, ArsR; SPTR: Regulatory protein ArsR.
  
    0.727
AEJ60537.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.718
AEJ60923.1
PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: sta:STHERM_c06290 iron-dependent repressor; PFAM: Iron dependent repressor; SMART: Iron dependent repressor; SPTR: Iron (Metal) dependent repressor, DtxR family.
  
  
 0.681
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.677
AEJ62189.1
Ferritin Dps family protein; PFAM: Ferritin-like domain; COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR008331; KEGG: sta:STHERM_c18850 DNA protection during starvation protein; PFAM: Ferritin/Dps protein; SPTR: Ferritin Dps family protein; Belongs to the Dps family.
  
  
 0.655
AEJ62187.1
PFAM: Putative RNA methylase family UPF0020; COGs: COG0116 N6-adenine-specific DNA methylase; InterPro IPR000241; KEGG: sta:STHERM_c18840 hypothetical protein; PFAM: Putative RNA methylase; SPTR: rRNA (Guanine-N(2)-)-methyltransferase.
  
    0.638
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.620
AEJ61524.1
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 0.614
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.613
AEJ60915.1
PFAM: ABC transporter; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c06210 ABC transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
  
  
 0.574
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.