Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62193.1PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006102:IPR006103; KEGG: sta:STHERM_c18890 carbohydrate binding family 6; PFAM: Glycoside hydrolase family 2, carbohydrate-binding; Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich; Glycoside hydrolase family 2, TIM barrel; SPTR: Glycoside hydrolase family 2 sugar binding. (1141 aa)    
Predicted Functional Partners:
AEJ60532.1
PFAM: Glycosyl hydrolase family 20, catalytic domain; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015883; KEGG: sta:STHERM_c02640 glycoside hydrolase, family 20; PFAM: Glycoside hydrolase, family 20, catalytic core; SPTR: Glycoside hydrolase, family 20, catalytic core.
 
 0.941
AEJ61792.1
PFAM: O-Glycosyl hydrolase family 30; COGs: COG5520 O-Glycosyl hydrolase; InterPro IPR001139; KEGG: fno:Fnod_0296 glucan endo-1,6-beta-glucosidase; PFAM: Glycoside hydrolase, family 30; SPTR: Glucan endo-1,6-beta-glucosidase; manually curated; Belongs to the glycosyl hydrolase 30 family.
 
 
 0.940
AEJ60642.1
Glycoside hydrolase family 42 domain protein; PFAM: Beta-galactosidase trimerisation domain; Beta-galactosidase C-terminal domain; Beta-galactosidase; COGs: COG1874 Beta-galactosidase; InterPro IPR013529:IPR013738:IPR013739; KEGG: sta:STHERM_c03920 beta-galactosidase; PFAM: Glycoside hydrolase, family 42, N-terminal; Beta-galactosidase trimerisation; Beta-galactosidase C-terminal; SPTR: Beta-galactosidase.
 
 
 0.931
AEJ60524.1
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
 
 
 0.924
AEJ60646.1
Glycoside hydrolase clan GH-D; PFAM: Melibiase; COGs: COG3345 Alpha-galactosidase; InterPro IPR000111; KEGG: sta:STHERM_c03960 alpha-galactosidase; PFAM: Glycoside hydrolase, clan GH-D; SPTR: Glycoside hydrolase clan GH-D.
  
 
 0.913
AEJ60528.1
PFAM: Aldose 1-epimerase; COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: sta:STHERM_c02600 aldose-epimerase; PFAM: Aldose 1-epimerase; SPTR: Aldose 1-epimerase.
  
 
 0.909
AEJ60931.1
PFAM: Glucokinase; TIGRFAM: glucokinase, proteobacterial type; COGs: COG0837 Glucokinase; InterPro IPR003836; KEGG: sta:STHERM_c06370 glucokinase; PFAM: Glucokinase; SPTR: Glucokinase.
     
 0.904
araA
L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.
     
 0.901
xylA
PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase; COGs: COG2115 Xylose isomerase; HAMAP: Xylose isomerase; InterPro IPR013452:IPR012307:IPR001998; KEGG: sta:STHERM_c16290 xylose isomerase; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase; TIGRFAM: Xylose isomerase, bacterial type; Belongs to the xylose isomerase family.
    
 0.810
AEJ60667.1
KEGG: sta:STHERM_c04180 alpha-L-fucosidase 2 precursor; SPTR: Alpha-L-fucosidase.
  
   
 0.718
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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