STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62196.1PFAM: Transglycosylase SLT domain; COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: sta:STHERM_c18920 hypothetical protein; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Lytic transglycosylase catalytic. (248 aa)    
Predicted Functional Partners:
AEJ61659.1
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.828
AEJ62195.1
Phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Prephenate dehydratase; ACT domain; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR001086:IPR002912:IPR006268; KEGG: sta:STHERM_c18910 hypothetical protein; PFAM: DAHP synthetase I/KDSA; Prephenate dehydratase; Amino acid-binding ACT; SPTR: Phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2.
       0.805
AEJ61208.1
PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sta:STHERM_c09090 flagellar hook-basal body complex protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: Flagellar hook-basal body complex protein FliE.
 
  
 0.779
AEJ60625.1
KEGG: sta:STHERM_c03720 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.757
AEJ61215.1
PFAM: Flagellar hook-length control protein FliK; InterPro IPR001635; KEGG: sta:STHERM_c09160 hypothetical protein; PFAM: Flagellar hook-length control protein; SPTR: Flagellar hook-length control protein-like, C-terminal domain.
 
    0.751
AEJ62173.1
KEGG: sta:STHERM_c18710 cytoskeletal protein; SPTR: Putative uncharacterized protein.
 
   
 0.747
AEJ62439.1
KEGG: sta:STHERM_c21410 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.739
AEJ61379.1
OmpA/MotB domain protein; PFAM: OmpA family; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: sta:STHERM_c10790 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA/MotB domain protein.
  
   
 0.734
AEJ61658.1
PFAM: FlaG protein; InterPro IPR005186; KEGG: sta:STHERM_c07720 hypothetical protein; PFAM: Flagellar protein FlaG protein; SPTR: Flagellar protein FlaG protein.
  
    0.717
AEJ61251.1
Protein serine/threonine phosphatase with extracellular sensor; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: sta:STHERM_c09530 HAMP domain-containing protein; PFAM: Sporulation stage II, protein E C-terminal; HAMP linker domain; SMART: Protein phosphatase 2C-related; HAMP linker domain; SPTR: Protein serine/threonine phosphatase.
  
     0.712
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.