STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62204.1KEGG: sta:STHERM_c19000 cytoplasmic protein; SPTR: Putative uncharacterized protein. (235 aa)    
Predicted Functional Partners:
fusA-2
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
 
     0.895
AEJ60377.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: sta:STHERM_c01030 transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; SMART: Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 1, dimer [...]
   
 
 0.759
AEJ60544.1
PFAM: Uncharacterised protein family (UPF0158); KEGG: sta:STHERM_c02740 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.740
AEJ61456.1
PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PPIC-type PPIASE domain; InterPro IPR000297; KEGG: sta:STHERM_c11500 hypothetical protein; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase.
  
     0.740
AEJ62522.1
Glycoside hydrolase family 37; PFAM: Trehalase; COGs: COG1626 Neutral trehalase; InterPro IPR001661; KEGG: sta:STHERM_c22220 hypothetical protein; PFAM: Glycoside hydrolase, family 37; SPTR: Glycoside hydrolase family 37.
  
     0.662
AEJ61773.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594; KEGG: sta:STHERM_c13770 histidine kinase; PFAM: ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Histidine kinase.
   
 
 0.661
AEJ62448.1
Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: sta:STHERM_c21500 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: [...]
   
 
 0.661
AEJ60494.1
KEGG: sta:STHERM_c02240 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.645
AEJ61626.1
Protein of unknown function YGGT; PFAM: YGGT family; InterPro IPR003425; KEGG: sta:STHERM_c08080 hypothetical protein; PFAM: Protein of unknown function YGGT; SPTR: Putative uncharacterized protein.
  
     0.639
AEJ60843.1
PFAM: Colicin V production protein; InterPro IPR003825; KEGG: sta:STHERM_c05410 hypothetical protein; PFAM: Colicin V production protein; SPTR: Colicin V production protein.
  
     0.631
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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