STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62206.1PFAM: CBS domain; COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644:IPR002912; KEGG: sta:STHERM_c19020 CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; Amino acid-binding ACT; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain containing protein. (214 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.759
AEJ62208.1
PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c19040 branched-chain amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family.
 
     0.713
AEJ62210.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: sta:STHERM_c19060 hypothetical protein; PFAM: Bacterial inner-membrane translocator; SPTR: Amino acid/amide ABC transporter membrane protein 1, HAAT family.
 
     0.713
AEJ62209.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: sta:STHERM_c19050 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator.
 
     0.704
AEJ62207.1
PFAM: ABC transporter; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c19030 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.
 
     0.703
AEJ62211.1
Extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: sta:STHERM_c19070 hypothetical protein; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor.
 
     0.590
fusA-2
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
       0.458
AEJ62204.1
KEGG: sta:STHERM_c19000 cytoplasmic protein; SPTR: Putative uncharacterized protein.
       0.444
AEJ60740.1
Acid phosphatase/vanadium-dependent haloperoxidase related protein; PFAM: Divergent PAP2 family; COGs: COG1963 conserved hypothetical protein; InterPro IPR003832; KEGG: sta:STHERM_c04390 hypothetical protein; PFAM: Acid phosphatase/vanadium-dependent haloperoxidase related; SPTR: Acid phosphatase/vanadium-dependent haloperoxidase related protein.
 
     0.427
AEJ60761.1
PFAM: Histone deacetylase domain; COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: sta:STHERM_c18020 histone deacetylase superfamily; PFAM: Histone deacetylase superfamily; SPTR: Histone deacetylase superfamily.
  
  
 0.421
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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