STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62222.1PFAM: Domain of unknown function DUF77; TIGRFAM: uncharacterized protein, MTH1187 family; COGs: COG0011 conserved hypothetical protein; InterPro IPR002767; KEGG: cac:CA_C1398 hypothetical protein; PFAM: Protein of unknown function DUF77; SPTR: Putative uncharacterized protein. (95 aa)    
Predicted Functional Partners:
AEJ62220.1
Hypothetical protein; PFAM: NMT1/THI5 like; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; InterPro IPR015168; KEGG: sta:STHERM_c19160 hypothetical protein; SPTR: Putative nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein.
 
     0.949
AEJ62221.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c19180 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.
 
    0.945
AEJ62219.1
PFAM: ABC transporter; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c19150 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
     0.853
AEJ62223.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Cache domain; HAMP domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterProIPR013163:IPR003660:IPR013767:IPR000160:IPR 001633:IPR000014; KEGG: sta:STHERM_c19190 hypothetical protein; PFAM: Diguanylate cyclase, predicted; HAMP linker domain; Cache, type 2; PAS fold; Diguanylate phosphodiesterase, predicted; SMART: Diguanylate cyclase, predicted; HAMP linker domain; PAS; Diguanylate phosphodiesterase, predicted; SPTR: Diguanylate [...]
       0.542
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
       0.449
AEJ62287.1
Hypothetical protein; PFAM: FMN-binding domain; KEGG: sta:STHERM_c19800 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.449
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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