STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62241.1Hypothetical protein; PFAM: Yip1 domain; KEGG: sta:STHERM_c19370 hypothetical protein; SPTR: Putative uncharacterized protein. (254 aa)    
Predicted Functional Partners:
AEJ62240.1
PFAM: Outer membrane efflux protein; KEGG: sta:STHERM_c19360 hypothetical protein; SPTR: Outer membrane efflux protein.
       0.773
AEJ62236.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sta:STHERM_c19320 transporter; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
       0.645
AEJ62237.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sta:STHERM_c19330 ABC-type transport system, permease; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
       0.645
macB
ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
       0.645
AEJ62239.1
PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: sta:STHERM_c19350 efflux transporter, RND family, MFP subunit; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.645
AEJ62242.1
PFAM: Histidine kinase; 5TMR of 5TMR-LYT; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3920 Signal transduction histidine kinase; InterProIPR011620:IPR013767:IPR011495:IPR003594:IPR 000014:IPR001610; KEGG: sta:STHERM_c19380 hypothetical protein; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; PAS fold; Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; ATP-binding region, ATPase-like; SMART: PAS; PAC motif; ATP-binding region, ATPase-like; SPTR: Signal [...]
       0.526
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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