STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62249.1Cof-like hydrolase; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB; COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: sta:STHERM_c19450 Cof-like hydrolase; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: Cof-like hydrolase; TIGRFAM: Cof protein; HAD-superfamily hydrolase, subfamily IIB. (271 aa)    
Predicted Functional Partners:
AEJ62250.1
PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: atm:ANT_29660 putative nitroreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase.
       0.776
AEJ62251.1
Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; COGs: COG1409 phosphohydrolase; InterPro IPR004843; KEGG: sta:STHERM_c19460 hypothetical protein; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase.
       0.559
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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