STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62250.1PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: atm:ANT_29660 putative nitroreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase. (175 aa)    
Predicted Functional Partners:
AEJ62249.1
Cof-like hydrolase; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB; COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: sta:STHERM_c19450 Cof-like hydrolase; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: Cof-like hydrolase; TIGRFAM: Cof protein; HAD-superfamily hydrolase, subfamily IIB.
       0.776
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.608
AEJ62251.1
Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; COGs: COG1409 phosphohydrolase; InterPro IPR004843; KEGG: sta:STHERM_c19460 hypothetical protein; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase.
       0.556
AEJ61155.1
Abortive infection protein; PFAM: CAAX amino terminal protease family; InterPro IPR003675; KEGG: sta:STHERM_c12770 hypothetical protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein.
  
  
 0.471
AEJ62264.1
PFAM: ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sta:STHERM_c19580 transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
  
 0.441
AEJ62265.1
PFAM: ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sta:STHERM_c19590 transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
  
 0.441
AEJ62332.1
PFAM: ABC-2 type transporter; TIGRFAM: ABC-2 type transporter, NodJ family; InterPro IPR013525; KEGG: sta:STHERM_c20340 ABC-type Nod factor export system, permease; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
  
 0.441
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
     
 0.422
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
  
  
 0.401
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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