STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62253.1PFAM: Amino acid permease; COGs: COG0531 Amino acid transporter; InterPro IPR004841; KEGG: sta:STHERM_c19480 solute carrier family 12 member 7; PFAM: Amino acid permease-associated region; SPTR: Amino acid permease-associated region. (744 aa)    
Predicted Functional Partners:
AEJ62252.1
KEGG: sta:STHERM_c19470 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.737
AEJ60307.1
PFAM: Alpha amylase, catalytic domain; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: sta:STHERM_c00200 hypothetical protein; PFAM: Glycosyl hydrolase, family 13, catalytic region; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha amylase catalytic region.
   
 0.660
AEJ60999.1
PFAM: Alpha amylase, catalytic domain; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: sta:STHERM_c15010 oligo-1,6-glucosidase; PFAM: Glycosyl hydrolase, family 13, catalytic region; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha amylase catalytic region.
   
 0.660
AEJ61152.1
Alpha amylase catalytic region; Catalyzes the reversible phosphorolysis of glucosylglycerate into alpha-D-glucose 1-phosphate (Glc1P) and D-glycerate. May be a regulator of intracellular levels of glucosylglycerate, a compatible solute that primarily protects organisms facing salt stress and very specific nutritional constraints. Cannot catalyze the phosphorolysis of sucrose.
   
 0.660
AEJ61918.1
PFAM: Alpha-amylase C-terminal beta-sheet domain; Alpha amylase, catalytic domain; COGs: COG0366 Glycosidase; InterPro IPR006589:IPR012850:IPR006047; KEGG: sta:STHERM_c15980 alpha-amylase type A isozyme precursor; PFAM: Glycosyl hydrolase, family 13, catalytic region; Alpha-amylase, C-terminal beta-sheet; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; Alpha-amylase, C-terminal beta-sheet; SPTR: Alpha amylase catalytic region.
   
 0.660
secF
Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
     
 0.561
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
     
 0.559
yajC
Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
     
 0.529
AEJ62280.1
Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR000089:IPR 013751:IPR013747; KEGG: sta:STHERM_c19760 hypothetical protein; PFAM: Tr [...]
 
  
 0.496
trpF
PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate (PRA) isomerase; COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR001240; KEGG: sta:STHERM_c01830 anthranilate synthase component; PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate isomerase (PRAI); SPTR: Indole-3-glycerol phosphate synthase; Belongs to the TrpF family.
    
 
 0.474
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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