Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62258.1PFAM: Glycosyl transferases group 1; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: sta:STHERM_c19520 hypothetical protein; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1. (387 aa)    
Predicted Functional Partners:
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.923
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.770
AEJ61917.1
Glycoside hydrolase family 13 domain protein; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); InterPro IPR004193; KEGG: sta:STHERM_c15960 hypothetical protein; PFAM: Glycoside hydrolase, family 13, N-terminal; SPTR: Glycoside hydrolase family 13 domain protein.
  
 0.637
AEJ62259.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c19530 hypothetical protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
     
 0.570
AEJ62260.1
PFAM: Outer membrane efflux protein; COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: sta:STHERM_c19540 hypothetical protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein.
     
 0.568
AEJ62264.1
PFAM: ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sta:STHERM_c19580 transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
       0.567
AEJ62265.1
PFAM: ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sta:STHERM_c19590 transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
       0.567
AEJ62261.1
PFAM: HlyD family secretion protein; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: sta:STHERM_c19550 transmembrane transport protein; PFAM: Secretion protein HlyD; SPTR: Secretion protein HlyD family protein.
       0.558
AEJ62262.1
PFAM: ABC transporter; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c19560 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
       0.558
AEJ62263.1
PFAM: ABC transporter; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c19570 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
       0.558
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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