Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62260.1PFAM: Outer membrane efflux protein; COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: sta:STHERM_c19540 hypothetical protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein. (437 aa)    
Predicted Functional Partners:
AEJ62261.1
PFAM: HlyD family secretion protein; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: sta:STHERM_c19550 transmembrane transport protein; PFAM: Secretion protein HlyD; SPTR: Secretion protein HlyD family protein.
 
 
 0.953
AEJ61305.1
TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR000089:IPR006143; KEGG: sta:STHERM_c10080 efflux transporter, RND family, MFP subunit; PFAM: Biotin/lipoyl attachment; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD.
  
 0.864
AEJ62468.1
TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: sta:STHERM_c21660 membrane fusion protein; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.864
AEJ62265.1
PFAM: ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sta:STHERM_c19590 transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
 
   
 0.846
AEJ62264.1
PFAM: ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sta:STHERM_c19580 transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
 
   
 0.845
AEJ62259.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c19530 hypothetical protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
 
   
 0.839
AEJ62262.1
PFAM: ABC transporter; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c19560 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
   
 0.824
AEJ62263.1
PFAM: ABC transporter; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c19570 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
   
 0.818
AEJ62469.1
Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: sta:STHERM_c21670 acriflavine resistance protein; PFAM: Acriflavin resistance protein; SPTR: Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.732
AEJ62239.1
PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: sta:STHERM_c19350 efflux transporter, RND family, MFP subunit; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.728
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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