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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62270.1KEGG: sta:STHERM_c19650 hypothetical protein; SPTR: Putative uncharacterized protein. (72 aa)    
Predicted Functional Partners:
AEJ62266.1
Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: sta:STHERM_c19600 dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase complex (E2); PFAM: 2-oxoacid dehydrogenase acyltransfer [...]
       0.449
AEJ62267.1
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
       0.449
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
       0.449
AEJ62269.1
PFAM: Pyridoxamine 5'-phosphate oxidase; COGs: COG3871 Uncharacterized stress protein (general stress protein 26); InterPro IPR011576; KEGG: sta:STHERM_c19630 hypothetical protein; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein.
       0.449
htpG
Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
       0.448
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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