STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AEJ62274.1PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: SurA N-terminal domain; PPIC-type PPIASE domain; COGs: COG0760 Parvulin-like peptidyl-prolyl isomerase; InterPro IPR015391:IPR000297; KEGG: sta:STHERM_c19690 PPIC-type PPIase domain-containing protein; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SurA N-terminal; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase. (336 aa)    
Predicted Functional Partners:
AEJ62275.1
PFAM: MatE; TIGRFAM: putative efflux protein, MATE family; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: sta:STHERM_c19700 hypothetical protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE.
   
   0.615
AEJ61427.1
PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein; COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184:IPR016474; KEGG: sta:STHERM_c11250 surface antigen; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Outer membrane protein assembly complex, YaeT protein; TIGRFAM: Outer membrane assembly protein, YaeT.
  
 
 0.554
AEJ61709.1
KEGG: sta:STHERM_c07110 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 
 0.524
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.451
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
 
 
 
 0.435
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
   
 
 0.429
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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