STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62275.1PFAM: MatE; TIGRFAM: putative efflux protein, MATE family; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: sta:STHERM_c19700 hypothetical protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE. (461 aa)    
Predicted Functional Partners:
AEJ62099.1
Hypothetical protein; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); KEGG: sta:STHERM_c17700 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 
 0.625
AEJ61097.1
PFAM: MatE; TIGRFAM: putative efflux protein, MATE family; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: sta:STHERM_c13350 hypothetical protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE.
  
     0.611
AEJ62274.1
PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: SurA N-terminal domain; PPIC-type PPIASE domain; COGs: COG0760 Parvulin-like peptidyl-prolyl isomerase; InterPro IPR015391:IPR000297; KEGG: sta:STHERM_c19690 PPIC-type PPIase domain-containing protein; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SurA N-terminal; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase.
   
   0.610
AEJ62511.1
PFAM: MatE; TIGRFAM: putative efflux protein, MATE family; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: sta:STHERM_c22110 hypothetical protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: Putative uncharacterized protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; manually curated.
  
     0.607
AEJ61276.1
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: sta:STHERM_c09790 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: Glyceraldehyde-3-p [...]
  
  
 0.600
cmk
PFAM: Cytidylate kinase; S1 RNA binding domain; TIGRFAM: ribosomal protein S1; cytidylate kinase; COGs: COG0539 Ribosomal protein S1; HAMAP: Cytidylate kinase; InterPro IPR011994:IPR003029:IPR003136; KEGG: sta:STHERM_c10970 30S ribosomal protein S1; PFAM: Cytidylate kinase region; Ribosomal protein S1, RNA binding domain; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase.
  
    0.583
AEJ62280.1
Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR000089:IPR 013751:IPR013747; KEGG: sta:STHERM_c19760 hypothetical protein; PFAM: Tr [...]
   
 
 0.500
AEJ62278.1
Major facilitator superfamily MFS_1; PFAM: Vacuole effluxer Atg22 like; COGs: COG2270 Permease of the major facilitator superfamily; InterPro IPR011701; KEGG: sta:STHERM_c19740 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1.
     
 0.491
pyrC
Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
     
 0.479
AEJ62277.1
KEGG: sta:STHERM_c19730 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.477
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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