STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62278.1Major facilitator superfamily MFS_1; PFAM: Vacuole effluxer Atg22 like; COGs: COG2270 Permease of the major facilitator superfamily; InterPro IPR011701; KEGG: sta:STHERM_c19740 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1. (424 aa)    
Predicted Functional Partners:
AEJ62277.1
KEGG: sta:STHERM_c19730 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.809
pyrC
Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
       0.777
AEJ62279.1
PFAM: Peptidase M16C associated; Peptidase M16 inactive domain; COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR007863:IPR013578; KEGG: sta:STHERM_c19750 presequence protease 1; PFAM: Peptidase M16C associated; Peptidase M16, C-terminal; SPTR: Peptidase M16C associated domain protein.
       0.554
AEJ62275.1
PFAM: MatE; TIGRFAM: putative efflux protein, MATE family; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: sta:STHERM_c19700 hypothetical protein; PFAM: Multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE.
     
 0.491
AEJ61812.1
KEGG: sta:STHERM_c14130 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.415
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.