STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62287.1Hypothetical protein; PFAM: FMN-binding domain; KEGG: sta:STHERM_c19800 hypothetical protein; SPTR: Putative uncharacterized protein. (283 aa)    
Predicted Functional Partners:
AEJ62290.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: sta:STHERM_c19840 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
 
  
 0.662
AEJ62288.1
PFAM: UbiA prenyltransferase family; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: sta:STHERM_c19810 hypothetical protein; PFAM: UbiA prenyltransferase; SPTR: UbiA prenyltransferase.
 
     0.627
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.584
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.584
AEJ60386.1
KEGG: sta:STHERM_c01120 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.504
AEJ62222.1
PFAM: Domain of unknown function DUF77; TIGRFAM: uncharacterized protein, MTH1187 family; COGs: COG0011 conserved hypothetical protein; InterPro IPR002767; KEGG: cac:CA_C1398 hypothetical protein; PFAM: Protein of unknown function DUF77; SPTR: Putative uncharacterized protein.
  
     0.449
AEJ62099.1
Hypothetical protein; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); KEGG: sta:STHERM_c17700 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.420
AEJ60941.1
PFAM: Heptaprenyl diphosphate synthase component I; COGs: COG4769 membrane protein; InterPro IPR010898; KEGG: sta:STHERM_c06470 hypothetical protein; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: Heptaprenyl diphosphate synthase component I.
 
     0.410
AEJ61048.1
PFAM: Protein of unknown function (DUF1576); InterPro IPR011470; KEGG: sbu:SpiBuddy_2939 hypothetical protein; PFAM: Protein of unknown function DUF1576; SPTR: Putative uncharacterized protein.
  
     0.402
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.