Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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AEJ62289.1PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: sta:STHERM_c19820 heptaprenyl diphosphate synthase component II; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (327 aa)    
Predicted Functional Partners:
AEJ62290.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: sta:STHERM_c19840 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
 
  
 0.928
AEJ62099.1
Hypothetical protein; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); KEGG: sta:STHERM_c17700 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.595
AEJ62288.1
PFAM: UbiA prenyltransferase family; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: sta:STHERM_c19810 hypothetical protein; PFAM: UbiA prenyltransferase; SPTR: UbiA prenyltransferase.
 
   
 0.526
AEJ62063.1
PFAM: Nucleoside diphosphate kinase; COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: sta:STHERM_c17330 nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase, core; SMART: Nucleoside diphosphate kinase, core; SPTR: Nucleoside diphosphate kinase; Belongs to the NDK family.
 
 
 0.522
AEJ62291.1
MOFRL domain protein; PFAM: MOFRL family; COGs: COG2379 Putative glycerate kinase; InterPro IPR007835; KEGG: sta:STHERM_c19830 hypothetical protein; PFAM: MOFRL; SPTR: Hydroxypyruvate reductase.
       0.520
AEJ60893.1
D-alanine--D-alanine ligase domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
 
 0.509
AEJ61123.1
Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
  
 0.498
AEJ61004.1
Methyltransferase type 11; PFAM: Methyltransferase domain; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: sta:STHERM_c14930 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11.
 
 
 0.495
xseB
Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
  
 0.491
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
    0.450
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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