Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEJ62290.1PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: sta:STHERM_c19840 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase. (656 aa)    
Predicted Functional Partners:
AEJ62289.1
PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: sta:STHERM_c19820 heptaprenyl diphosphate synthase component II; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.928
AEJ60919.1
PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575; KEGG: sta:STHERM_c06250 NADH-quinone oxidoreductase subunit 1; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: NADH dehydrogenase (Quinone).
     
 0.925
AEJ60918.1
PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit; COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: sta:STHERM_c06240 NADH-quinone oxidoreductase subunit E; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; SPTR: NADH-quinone oxidoreductase, E subunit; TIGRFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit.
     
 0.906
AEJ61774.1
PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: sta:STHERM_c13780 hypothetical protein; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; SPTR: NAD(P)-dependent iron-only hydrogenase diaphorase component iron-sulfur protein.
     
 0.906
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
  
 0.701
AEJ62288.1
PFAM: UbiA prenyltransferase family; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: sta:STHERM_c19810 hypothetical protein; PFAM: UbiA prenyltransferase; SPTR: UbiA prenyltransferase.
 
  
 0.653
AEJ60732.1
PFAM: FMN-binding domain; COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: sta:STHERM_c18120 hypothetical protein; PFAM: FMN-binding; SPTR: FMN-binding domain protein.
 
    0.622
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
   0.598
AEJ62287.1
Hypothetical protein; PFAM: FMN-binding domain; KEGG: sta:STHERM_c19800 hypothetical protein; SPTR: Putative uncharacterized protein.
 
    0.583
AEJ60941.1
PFAM: Heptaprenyl diphosphate synthase component I; COGs: COG4769 membrane protein; InterPro IPR010898; KEGG: sta:STHERM_c06470 hypothetical protein; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: Heptaprenyl diphosphate synthase component I.
 
     0.569
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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