STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62292.1PFAM: PTS system sugar-specific permease component; COGs: COG3775 Phosphotransferase system galactitol-specific IIC component; InterPro IPR004703; KEGG: sta:STHERM_c19850 hypothetical protein; PFAM: Phosphotransferase system, galactitol-specific IIC component; SPTR: PTS system Galactitol-specific IIC component. (451 aa)    
Predicted Functional Partners:
AEJ62498.1
Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein.
    
 0.910
AEJ62080.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611; KEGG: sta:STHERM_c17500 sugar kinase; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
 
  
 0.901
gatA
Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
   
    0.835
AEJ61591.1
PFAM: Bacterial alpha-L-rhamnosidase; Alpha-L-rhamnosidase N-terminal domain; InterPro IPR013737:IPR008902; KEGG: sta:STHERM_c08460 alfa-L-rhamnosidase; PFAM: Bacterial alpha-L-rhamnosidase; Bacterial alpha-L-rhamnosidase N-terminal; SPTR: Alpha-L-rhamnosidase.
   
    0.830
AEJ60366.1
PFAM: F5/8 type C domain; Cellulase (glycosyl hydrolase family 5); InterPro IPR000421; KEGG: sta:STHERM_c00920 hypothetical protein; PFAM: Coagulation factor 5/8 type, C-terminal; SPTR: Mannan endo-1,4-beta-mannosidase.
  
  
 0.612
AEJ60519.1
PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006103; KEGG: sta:STHERM_c02500 beta-mannosidase precursor; PFAM: Glycoside hydrolase family 2, carbohydrate-binding; Glycoside hydrolase family 2, TIM barrel; SPTR: Beta-mannosidase.
  
  
 0.612
AEJ62193.1
PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006102:IPR006103; KEGG: sta:STHERM_c18890 carbohydrate binding family 6; PFAM: Glycoside hydrolase family 2, carbohydrate-binding; Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich; Glycoside hydrolase family 2, TIM barrel; SPTR: Glycoside hydrolase family 2 sugar binding.
  
  
 0.612
AEJ60732.1
PFAM: FMN-binding domain; COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: sta:STHERM_c18120 hypothetical protein; PFAM: FMN-binding; SPTR: FMN-binding domain protein.
  
     0.608
AEJ62293.1
PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: sta:STHERM_c19860 bacterioferritin comigratory protein/NADH dehydrogenase; PFAM: Nitroreductase-like; SPTR: Nitroreductase.
       0.592
AEJ60896.1
PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: sta:STHERM_c06020 hypothetical protein; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; SPTR: Alcohol dehydrogenase GroES domain protein.
  
 0.526
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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