Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62293.1PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: sta:STHERM_c19860 bacterioferritin comigratory protein/NADH dehydrogenase; PFAM: Nitroreductase-like; SPTR: Nitroreductase. (192 aa)    
Predicted Functional Partners:
AEJ60372.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PFAM: AhpC/TSA family; COGs: COG1225 Peroxiredoxin; InterPro IPR000866; KEGG: sta:STHERM_c00980 peroxiredoxin bcp; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen.
    
 0.709
AEJ62294.1
Hypothetical protein; PFAM: Cellulase (glycosyl hydrolase family 5); KEGG: sta:STHERM_c19870 hypothetical protein; SPTR: Putative uncharacterized protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
       0.672
AEJ61881.1
PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: shg:Sph21_2015 nitroreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase.
  
     0.616
AEJ62292.1
PFAM: PTS system sugar-specific permease component; COGs: COG3775 Phosphotransferase system galactitol-specific IIC component; InterPro IPR004703; KEGG: sta:STHERM_c19850 hypothetical protein; PFAM: Phosphotransferase system, galactitol-specific IIC component; SPTR: PTS system Galactitol-specific IIC component.
       0.592
rpmE2
PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31; COGs: COG0254 Ribosomal protein L31; HAMAP: 50S ribosomal protein L31; InterPro IPR002150; KEGG: sta:STHERM_c19880 50S ribosomal protein L31; PFAM: Ribosomal protein L31; SPTR: 50S ribosomal protein L31 type B; TIGRFAM: Ribosomal protein L31.
  
    0.551
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.538
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
     
 0.533
AEJ61155.1
Abortive infection protein; PFAM: CAAX amino terminal protease family; InterPro IPR003675; KEGG: sta:STHERM_c12770 hypothetical protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein.
  
  
 0.460
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
  
  
 0.457
AEJ62299.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR013105:IPR019734; KEGG: sta:STHERM_c19920 hypothetical protein; PFAM: Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: Putative uncharacterized protein.
 
     0.454
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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