Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62294.1Hypothetical protein; PFAM: Cellulase (glycosyl hydrolase family 5); KEGG: sta:STHERM_c19870 hypothetical protein; SPTR: Putative uncharacterized protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (636 aa)    
Predicted Functional Partners:
AEJ62293.1
PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: sta:STHERM_c19860 bacterioferritin comigratory protein/NADH dehydrogenase; PFAM: Nitroreductase-like; SPTR: Nitroreductase.
       0.672
AEJ62212.1
Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; COGs: COG2236 phosphoribosyltransferase; InterPro IPR000836; KEGG: sta:STHERM_c19080 hypothetical protein; PFAM: Phosphoribosyltransferase; SPTR: Putative uncharacterized protein.
  
     0.648
AEJ62343.1
TIGRFAM: monofunctional chorismate mutase, eukaryotic type; InterPro IPR008238; KEGG: sta:STHERM_c20450 chorismate mutase; SPTR: Chorismate mutase; TIGRFAM: Chorismate mutase, AroQ class, eukaryotic type.
  
     0.643
rpmE2
PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31; COGs: COG0254 Ribosomal protein L31; HAMAP: 50S ribosomal protein L31; InterPro IPR002150; KEGG: sta:STHERM_c19880 50S ribosomal protein L31; PFAM: Ribosomal protein L31; SPTR: 50S ribosomal protein L31 type B; TIGRFAM: Ribosomal protein L31.
       0.623
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
       0.598
AEJ62300.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: sta:STHERM_c19930 transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
 
     0.556
AEJ62006.1
PFAM: Glycosyl Hydrolase Family 88; InterPro IPR010905; KEGG: sma:SAV_44 unsaturated glucuronyl hydrolase; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88.
  
 
 0.522
AEJ62292.1
PFAM: PTS system sugar-specific permease component; COGs: COG3775 Phosphotransferase system galactitol-specific IIC component; InterPro IPR004703; KEGG: sta:STHERM_c19850 hypothetical protein; PFAM: Phosphotransferase system, galactitol-specific IIC component; SPTR: PTS system Galactitol-specific IIC component.
       0.519
AEJ60492.1
Multi-sensor hybrid histidine kinase; PFAM: 7TM diverse intracellular signalling; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: sta:STHERM_c02220 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, p [...]
 
   
 0.493
AEJ62363.1
Glycoside hydrolase family 9; PFAM: Cellulose binding domain; Glycosyl hydrolase family 9; InterPro IPR001701:IPR001956; KEGG: sta:STHERM_c20640 glycoside hydrolase family 9, CBM3, linker, domain X; PFAM: Glycoside hydrolase, family 9; Bacterial type 3a, cellulose-binding; SPTR: Cellulase.
   
 
 0.459
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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