STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62297.1Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136:IPR008135; KEGG: sta:STHERM_c19900 CinA-like protein; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal. (420 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.959
AEJ61716.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.942
AEJ61335.1
Nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638:IPR004393; KEGG: sta:STHERM_c10350 hypothetical protein; PFAM: Quinolinate phosphoribosyl transferase; SPTR: Nicotinate-nucleotide pyrophosphorylase; TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
    
 0.937
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.916
AEJ60895.1
PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR004570:IPR000462; KEGG: sta:STHERM_c06010 hypothetical protein; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.897
AEJ61913.1
PFAM: CDP-alcohol phosphatidyltransferase; InterPro IPR000462; KEGG: sta:STHERM_c15930 CDP-alcohol phosphatidyltransferase family protein; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.897
AEJ62299.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR013105:IPR019734; KEGG: sta:STHERM_c19920 hypothetical protein; PFAM: Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: Putative uncharacterized protein.
       0.808
AEJ62300.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: sta:STHERM_c19930 transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
  
  
 0.790
AEJ62298.1
PFAM: Protein of unknown function, DUF583; COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: sta:STHERM_c19910 hypothetical protein; PFAM: Protein of unknown function DUF583; SPTR: Putative uncharacterized protein.
       0.787
AEJ60859.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: sta:STHERM_c05590 2-hydroxyacid dehydrogenase-like protein 2; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding.
  
    0.701
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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