STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62321.1PFAM: 4Fe-4S binding domain; InterPro IPR001450; KEGG: sta:STHERM_c20140 hypothetical protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Iron-sulfur cluster-binding protein. (277 aa)    
Predicted Functional Partners:
AEJ61770.1
Hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR019574:IPR001450:IPR004108:IPR 003149:IPR013352; KEGG: sta:STHERM_c13740 hypothetical protein; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulp [...]
   
 
 0.709
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
 
   
 0.707
AEJ61537.1
Hypothetical protein; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; KEGG: sta:STHERM_c12340 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 
 0.607
AEJ61540.1
Hypothetical protein; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; KEGG: sta:STHERM_c12370 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 
 0.593
AEJ62320.1
Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: sta:STHERM_c20130 hypothetical protein; PFAM: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SMART: HTH transcriptional regulator, Crp; SPTR: Transcriptional regulator, Crp/Fnr family.
       0.588
AEJ60918.1
PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit; COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: sta:STHERM_c06240 NADH-quinone oxidoreductase subunit E; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; SPTR: NADH-quinone oxidoreductase, E subunit; TIGRFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit.
   
 
 0.506
AEJ61774.1
PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: sta:STHERM_c13780 hypothetical protein; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; SPTR: NAD(P)-dependent iron-only hydrogenase diaphorase component iron-sulfur protein.
   
 
 0.506
AEJ60497.1
Protein of unknown function DUF1121; PFAM: Uncharacterised ACR, YkgG family COG1556; InterPro IPR009501; KEGG: sta:STHERM_c02270 hypothetical protein; PFAM: Protein of unknown function DUF1121; SPTR: Putative uncharacterized protein.
  
 
   0.478
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
     
 0.439
AEJ62332.1
PFAM: ABC-2 type transporter; TIGRFAM: ABC-2 type transporter, NodJ family; InterPro IPR013525; KEGG: sta:STHERM_c20340 ABC-type Nod factor export system, permease; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
     0.401
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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