STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hcpHydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (552 aa)    
Predicted Functional Partners:
AEJ60553.1
PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I; COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: sta:STHERM_c02830 glutamine synthetase, type 1; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp; SPTR: Glutamine synthetase; TIGRFAM: Glutamine synthetase type I.
     
 0.901
AEJ62321.1
PFAM: 4Fe-4S binding domain; InterPro IPR001450; KEGG: sta:STHERM_c20140 hypothetical protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Iron-sulfur cluster-binding protein.
 
   
 0.707
AEJ62320.1
Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: sta:STHERM_c20130 hypothetical protein; PFAM: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SMART: HTH transcriptional regulator, Crp; SPTR: Transcriptional regulator, Crp/Fnr family.
 
   
 0.675
AEJ60873.1
Rieske (2Fe-2S) iron-sulfur domain-containing protein; PFAM: Rieske [2Fe-2S] domain; COGs: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase; InterPro IPR017941; KEGG: sta:STHERM_c05740 hypothetical protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Putative uncharacterized protein.
   
    0.599
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
     
 0.558
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
  
 0.555
AEJ60986.1
PFAM: Dinitrogenase iron-molybdenum cofactor; COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: sta:STHERM_c15140 hypothetical protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Putative uncharacterized protein; manually curated.
  
     0.473
AEJ60777.1
Hypothetical protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG0426 flavoprotein; KEGG: sta:STHERM_c04740 hypothetical protein; SPTR: Uncharacterized flavoprotein.
 
   
 0.413
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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