STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62326.1RCC1 repeats protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; KEGG: sta:STHERM_c20190 RCC1 repeats protein; SPTR: Regulator of chromosome condensation RCC1. (387 aa)    
Predicted Functional Partners:
AEJ62325.1
KEGG: sta:STHERM_c20180 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.631
AEJ60414.1
PFAM: TraB family; TIGRFAM: pheromone shutdown-related protein TraB; COGs: COG1916 Uncharacterized homolog of PrgY (pheromone shutdown protein); InterPro IPR002816:IPR005230; KEGG: sta:STHERM_c01390 TraB family protein; PFAM: Pheromone shutdown-related, TraB; SPTR: TraB family protein; TIGRFAM: Pheromone shutdown, TraB.
    
   0.595
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
   0.595
AEJ62327.1
MULE transposase, conserved domain-containing protein; Required for the transposition of the insertion element.
       0.570
AEJ61973.1
PFAM: 3-oxo-5-alpha-steroid 4-dehydrogenase; InterPro IPR001104; KEGG: sta:STHERM_c16540 3-oxo-5-alpha-steroid 4-dehydrogenase family protein; PFAM: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal; SPTR: 3-oxo-5-alpha-steroid 4-dehydrogenase.
  
     0.468
AEJ61724.1
PFAM: FHA domain; COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: sta:STHERM_c06930 hypothetical protein; PFAM: Forkhead-associated; SMART: Forkhead-associated; SPTR: FHA domain containing protein.
 
 
  0.458
AEJ62324.1
KEGG: sta:STHERM_c20160 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.455
AEJ61119.1
WD40 repeat-containing protein; PFAM: WD domain, G-beta repeat; InterPro IPR019781:IPR001680; KEGG: sta:STHERM_c13130 hypothetical protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat; SPTR: WD40 repeat, subgroup.
   
 0.445
AEJ62328.1
Transposase IS4 family protein; PFAM: Transposase DDE domain; Transposase domain (DUF772); InterPro IPR002559; KEGG: sta:STHERM_c20700 transposase of ISLsa3, OrfB; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein.
 
     0.426
AEJ60535.1
Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; InterPro IPR004843; KEGG: sta:STHERM_c02680 hydrolase; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase.
  
 
  0.409
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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