STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62333.1Protein of unknown function UPF0005; PFAM: Uncharacterised protein family UPF0005; COGs: COG0670 Integral membrane protein interacts with FtsH; InterPro IPR006214; KEGG: sta:STHERM_c20350 hypothetical protein; PFAM: Uncharacterised protein family UPF0005; SPTR: Putative uncharacterized protein; Belongs to the BI1 family. (234 aa)    
Predicted Functional Partners:
AEJ61711.1
PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR000014:IPR003661:IPR003594; KEGG: sta:STHERM_c07090 sensor protein ZraS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PA [...]
   
  
 0.484
AEJ62331.1
PFAM: ABC transporter; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c20330 Nod factor export ATP-binding protein I; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
  
   0.469
AEJ62332.1
PFAM: ABC-2 type transporter; TIGRFAM: ABC-2 type transporter, NodJ family; InterPro IPR013525; KEGG: sta:STHERM_c20340 ABC-type Nod factor export system, permease; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
       0.425
AEJ61803.1
PFAM: Peptidase family M48; COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: sta:STHERM_c14040 peptidase, M48 family; PFAM: Peptidase M48, Ste24p; SPTR: Peptidase M48 Ste24p.
  
  
 0.406
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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