STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62342.1PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839; KEGG: sta:STHERM_c20440 8-amino-7-oxononanoate synthase; PFAM: Aminotransferase, class I/II; SPTR: Serine palmitoyltransferase. (404 aa)    
Predicted Functional Partners:
AEJ61106.1
PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase; COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005814; KEGG: sta:STHERM_c13250 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: Aminotransferase class-III; SPTR: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; manually curated; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.974
AEJ61105.1
PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839; KEGG: sta:STHERM_c13260 hypothetical protein; PFAM: Aminotransferase, class I/II; SPTR: 8-amino-7-oxononanoate synthase.
  
  
 
0.922
AEJ61104.1
PFAM: Protein of unknown function (DUF452); COGs: COG2830 conserved hypothetical protein; InterPro IPR007398; KEGG: sta:STHERM_c13270 hypothetical protein; PFAM: Protein of unknown function DUF452; SPTR: Putative uncharacterized protein.
  
 
  0.909
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
  
 0.883
AEJ62341.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: sta:STHERM_c20430 follicular variant translocation protein 1 precursor; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.758
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 0.722
AEJ60767.1
PFAM: Radical SAM superfamily; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydE; COGs: COG0502 Biotin synthase; InterPro IPR006638:IPR007197; KEGG: sta:STHERM_c17990 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
  
  
 0.626
AEJ62339.1
PFAM: Bacterial extracellular solute-binding protein, family 7; COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR018389; KEGG: sta:STHERM_c20410 transporter; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: Extracellular solute-binding protein, family 7.
       0.621
AEJ62340.1
TRAP dicarboxylate transporter, DctM subunit; PFAM: DctM-like transporters; Tripartite ATP-independent periplasmic transporters, DctQ component; TIGRFAM: TRAP transporter, DctM subunit; COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR007387:IPR010656:IPR004681; KEGG: sta:STHERM_c20420 transporter; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: TRAP dicarboxylate transporter, DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit.
       0.621
AEJ62338.1
KEGG: sta:STHERM_c20400 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.593
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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