STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62343.1TIGRFAM: monofunctional chorismate mutase, eukaryotic type; InterPro IPR008238; KEGG: sta:STHERM_c20450 chorismate mutase; SPTR: Chorismate mutase; TIGRFAM: Chorismate mutase, AroQ class, eukaryotic type. (254 aa)    
Predicted Functional Partners:
AEJ62345.1
KEGG: ssm:Spirs_3055 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
 
     0.800
AEJ62344.1
PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1; COGs: COG1443 Isopentenyldiphosphate isomerase; InterPro IPR000086; KEGG: sta:STHERM_c20460 NUDIX hydrolase 3; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase.
       0.773
AEJ62294.1
Hypothetical protein; PFAM: Cellulase (glycosyl hydrolase family 5); KEGG: sta:STHERM_c19870 hypothetical protein; SPTR: Putative uncharacterized protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.643
AEJ61966.1
PFAM: Acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase; COGs: COG0059 Ketol-acid reductoisomerase; InterPro IPR013116:IPR000506; KEGG: sta:STHERM_c16450 ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase C-terminal; Acetohydroxy acid isomeroreductase, catalytic; SPTR: Acetohydroxy acid isomeroreductase.
  
     0.548
hppA
Pyrophosphate-energized proton pump; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
       0.533
AEJ60535.1
Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; InterPro IPR004843; KEGG: sta:STHERM_c02680 hydrolase; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase.
  
     0.478
AEJ62212.1
Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; COGs: COG2236 phosphoribosyltransferase; InterPro IPR000836; KEGG: sta:STHERM_c19080 hypothetical protein; PFAM: Phosphoribosyltransferase; SPTR: Putative uncharacterized protein.
  
     0.463
pyrC
Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
  
     0.459
AEJ60492.1
Multi-sensor hybrid histidine kinase; PFAM: 7TM diverse intracellular signalling; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: sta:STHERM_c02220 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, p [...]
  
     0.427
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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