Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62344.1PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1; COGs: COG1443 Isopentenyldiphosphate isomerase; InterPro IPR000086; KEGG: sta:STHERM_c20460 NUDIX hydrolase 3; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase. (174 aa)    
Predicted Functional Partners:
AEJ62343.1
TIGRFAM: monofunctional chorismate mutase, eukaryotic type; InterPro IPR008238; KEGG: sta:STHERM_c20450 chorismate mutase; SPTR: Chorismate mutase; TIGRFAM: Chorismate mutase, AroQ class, eukaryotic type.
       0.773
AEJ62345.1
KEGG: ssm:Spirs_3055 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
       0.773
AEJ62099.1
Hypothetical protein; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); KEGG: sta:STHERM_c17700 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.558
hppA
Pyrophosphate-energized proton pump; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
     
 0.534
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
    0.517
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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