Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEJ62355.1Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: sta:STHERM_c20560 ribose ABC transporter; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator. (318 aa)    
Predicted Functional Partners:
AEJ62354.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c20550 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Transporter.
 0.990
rbsA-3
ABC transporter related protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
 0.980
AEJ60708.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ebd:ECBD_0922 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Monosaccharide ABC transporter membrane protein, CUT2 family.
 0.978
rbsA
ABC transporter related protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
 0.961
AEJ60709.1
Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: pjd:Pjdr2_5327 periplasmic binding protein/LacI transcriptional regulator; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator.
  
  
 
0.920
AEJ61600.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c08350 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Monosaccharide ABC transporter membrane protein, CUT2 family.
 
 0.894
AEJ61601.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c08340 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator.
 
 
 0.892
AEJ60492.1
Multi-sensor hybrid histidine kinase; PFAM: 7TM diverse intracellular signalling; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: sta:STHERM_c02220 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, p [...]
   
 
 0.858
AEJ61090.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013656:IPR003661:IPR003594:IPR 001789:IPR008207; KEGG: sta:STHERM_c14170 two-component system, sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; Signal transduction response regulator, receiver region; Signal transducti [...]
   
 
 0.858
AEJ60416.1
Integral membrane sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: sta:STHERM_c01410 transcriptional regulatory protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine [...]
   
 
 0.832
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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