STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62356.1PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843; KEGG: sta:STHERM_c20570 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. (357 aa)    
Predicted Functional Partners:
AEJ62355.1
Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: sta:STHERM_c20560 ribose ABC transporter; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator.
 
  
 0.746
AEJ60542.1
PFAM: Bacterial regulatory proteins, luxR family; family; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR013767:IPR000792:IPR000014; KEGG: sta:STHERM_c02720 transcriptional regulator protein; PFAM: Transcription regulator LuxR, C-terminal; Periplasmic binding protein/LacI transcriptional regulator; PAS fold; SMART: Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator, LuxR family; TIGRFAM: PAS.
  
     0.740
AEJ62150.1
Transcriptional regulator, GntR family with LacI sensor; PFAM: Bacterial regulatory proteins, gntR family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000524:IPR001761; KEGG: sta:STHERM_c18490 transcriptional repressor; PFAM: HTH transcriptional regulator, GntR; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family with LacI sensor.
  
     0.721
AEJ61321.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit.
    
 
 0.680
araB
Ribulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: L-ribulokinase; COGs: COG1069 Ribulose kinase; HAMAP: L-ribulokinase; InterPro IPR018484:IPR018485:IPR005929; KEGG: sta:STHERM_c20530 ribulokinase; PFAM: Carbohydrate kinase, FGGY, C-terminal; Carbohydrate kinase, FGGY, N-terminal; SPTR: Ribulokinase.
 
  
 0.546
AEJ62498.1
Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein.
   
 
 0.545
araA
L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.
     
 0.539
AEJ60516.1
PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; family; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR004089; KEGG: sta:STHERM_c02460 transcriptional regulatory protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Periplasmic binding protein/LacI transcriptional regulator; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer.
  
     0.515
AEJ62354.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c20550 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Transporter.
  
  
 0.507
AEJ62350.1
Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: sta:STHERM_c20510 L-ribulose-5-phosphate 4-epimerase; PFAM: Class II aldolase/adducin, N-terminal; SPTR: L-ribulose 5-phosphate 4-epimerase.
     
 0.505
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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