STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62369.1Hypothetical protein; PFAM: Cellulase (glycosyl hydrolase family 5); KEGG: sta:STHERM_c20580 hypothetical protein; SPTR: Putative uncharacterized protein. (758 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
       0.540
AEJ62368.1
Dihydroorotate dehydrogenase electron transfer subunit; PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: sta:STHERM_c20590 oxidoreductase FAD/NAD(P)-binding domain-containing protein; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding [...]
       0.540
AEJ60667.1
KEGG: sta:STHERM_c04180 alpha-L-fucosidase 2 precursor; SPTR: Alpha-L-fucosidase.
  
     0.448
AEJ61710.1
PFAM: Cellulase (glycosyl hydrolase family 5); COGs: COG2730 Endoglucanase; InterPro IPR001547; KEGG: sta:STHERM_c07100 endoglucanase; PFAM: Glycoside hydrolase, family 5; SPTR: Glycoside hydrolase family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
   
 0.446
AEJ61963.1
PFAM: Domain of unknown function (DUF303); Glycosyl hydrolases family 2, sugar binding domain; InterPro IPR005181:IPR006104; KEGG: sta:STHERM_c16420 sialic acid-specific 9-O-acetylesterase; PFAM: Protein of unknown function DUF303, acetylesterase putative; Glycoside hydrolase family 2, carbohydrate-binding; SPTR: Putative uncharacterized protein.
 
     0.408
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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