STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62381.12'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (191 aa)    
Predicted Functional Partners:
AEJ62382.1
PFAM: NUDIX domain; InterPro IPR000086; KEGG: sta:STHERM_c20830 MutT/NUDIX family protein; PFAM: NUDIX hydrolase domain; SPTR: MutT/nudix family protein.
  
    0.789
AEJ62383.1
PFAM: Radical SAM superfamily; TIGRFAM: KamA family protein; COGs: COG1509 Lysine 2 3-aminomutase; InterPro IPR007197:IPR003739; KEGG: sta:STHERM_c20840 L-lysine 2,3-aminomutase; PFAM: Radical SAM; SPTR: Lysine 2,3-aminomutase YodO family protein; TIGRFAM: Protein of unknown function DUF160.
       0.778
AEJ62380.1
PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: sta:STHERM_c20810 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer.
       0.578
AEJ62384.1
KEGG: sta:STHERM_c20850 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.540
rtcB
Protein of unknown function UPF0027; PFAM: Uncharacterized protein family UPF0027; COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: sta:STHERM_c16050 hypothetical protein; PFAM: Uncharacterised protein family UPF0027; SPTR: Putative uncharacterized protein; Belongs to the RtcB family.
 
   
 0.452
AEJ62379.1
Hypothetical protein; PFAM: Hsp20/alpha crystallin family; KEGG: sta:STHERM_c20800 hypothetical protein; SPTR: Putative uncharacterized protein; Belongs to the small heat shock protein (HSP20) family.
       0.444
AEJ62385.1
PFAM: Aldo/keto reductase family; COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: sta:STHERM_c20860 hypothetical protein; PFAM: Aldo/keto reductase; SPTR: Aldo/keto reductase.
       0.441
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.439
AEJ62297.1
Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136:IPR008135; KEGG: sta:STHERM_c19900 CinA-like protein; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal.
     
 0.434
AEJ62197.1
PFAM: Glycosyl hydrolase family 10; COGs: COG3693 Beta-1 4-xylanase; InterPro IPR001000; KEGG: sta:STHERM_c18930 endo-1,4-beta-xylanase B precursor; PFAM: Glycoside hydrolase, family 10; SMART: Glycoside hydrolase, family 10; SPTR: Endo-1,4-beta-xylanase.
  
  
 0.412
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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