Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEJ62404.1PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR003313:IPR000005:IPR018060; KEGG: sta:STHERM_c21040 transcriptional regulatory protein; PFAM: AraC protein, arabinose-binding/dimerisation; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family. (304 aa)    
Predicted Functional Partners:
AEJ61587.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR018060:IPR000005; KEGG: sta:STHERM_c08500 transcriptional regulatory protein; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
 
 
 0.800
AEJ60652.1
Transcriptional regulator with cupin sensor, AraC family; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR013096:IPR000005; KEGG: sta:STHERM_c04010 transcriptional regulator, AraC/XylS family; PFAM: Helix-turn-helix, AraC type; Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
 
0.799
AEJ61487.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-type transcriptional regulator N-terminus; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR009594:IPR000005:IPR018060; KEGG: sta:STHERM_c11750 transcriptional regulator, AraC family; PFAM: AraC-type transcriptional regulator, N-terminal; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
 
0.683
AEJ62403.1
Beta-galactosidase; PFAM: Glycosyl hydrolase family 1; TIGRFAM: beta-galactosidase; COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR017736:IPR001360; KEGG: sta:STHERM_c21030 beta-glucosidase A; PFAM: Glycoside hydrolase, family 1; SPTR: Broad-specificity cellobiase; TIGRFAM: Glycoside hydrolase, family 1, beta-glucosidase.
     
 0.633
AEJ61888.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017475:IPR003362; KEGG: tth:TTC0275 undecaprenyl-phosphate galactosephosphotransferase; PFAM: Bacterial sugar transferase; SPTR: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
  
  
 0.588
AEJ60904.1
Cupin 2 conserved barrel domain protein; PFAM: Cupin domain; InterPro IPR013096; KEGG: sta:STHERM_c06100 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Cupin 2 conserved barrel domain protein.
 
 
 0.574
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 
 0.550
AEJ61620.1
PFAM: Polysaccharide biosynthesis protein; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: sta:STHERM_c08150 capsular polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein CapD-like; SPTR: Polysaccharide biosynthesis protein CapD.
  
  
 0.529
AEJ62401.1
KEGG: sta:STHERM_c21010 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.504
AEJ62402.1
PFAM: Glycosyltransferase family 36; Putative carbohydrate binding domain; Glycosyltransferase 36 associated family; COGs: COG3459 Cellobiose phosphorylase; InterPro IPR009342:IPR010383; KEGG: sta:STHERM_c21020 cellodextrin-phosphorylase; PFAM: Glycosyltransferase 36; Putative carbohydrate binding; SPTR: Cellobiose phosphorylase.
       0.504
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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