| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEJ60486.1 | AEJ62408.1 | Spith_0199 | Spith_2153 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: sta:STHERM_c21080 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein. | 0.458 |
| AEJ60727.1 | AEJ62408.1 | Spith_0444 | Spith_2153 | PFAM: Fe2+ transport protein; COGs: COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport; InterPro IPR018470; KEGG: sta:STHERM_c18170 hypothetical protein; PFAM: Ferrous iron transport protein, bacterial; SPTR: Ferrous iron transport protein. | PFAM: Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: sta:STHERM_c21080 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein. | 0.444 |
| AEJ60765.1 | AEJ61832.1 | Spith_0485 | Spith_1571 | Transcriptional regulator, CopG family; TIGRFAM: putative iron-only hydrogenase system regulator; KEGG: sta:STHERM_c18010 transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein. | KEGG: hypothetical protein; SPTR: Putative uncharacterized protein. | 0.466 |
| AEJ60765.1 | AEJ62407.1 | Spith_0485 | Spith_2152 | Transcriptional regulator, CopG family; TIGRFAM: putative iron-only hydrogenase system regulator; KEGG: sta:STHERM_c18010 transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein. | ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sta:STHERM_c21070 transporter; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein. | 0.938 |
| AEJ60765.1 | AEJ62408.1 | Spith_0485 | Spith_2153 | Transcriptional regulator, CopG family; TIGRFAM: putative iron-only hydrogenase system regulator; KEGG: sta:STHERM_c18010 transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein. | PFAM: Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: sta:STHERM_c21080 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein. | 0.936 |
| AEJ60981.1 | AEJ62408.1 | Spith_0702 | Spith_2153 | AAA ATPase; InterPro IPR003593; KEGG: sta:STHERM_c15210 hypothetical protein; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase. | PFAM: Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: sta:STHERM_c21080 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein. | 0.641 |
| AEJ61832.1 | AEJ60765.1 | Spith_1571 | Spith_0485 | KEGG: hypothetical protein; SPTR: Putative uncharacterized protein. | Transcriptional regulator, CopG family; TIGRFAM: putative iron-only hydrogenase system regulator; KEGG: sta:STHERM_c18010 transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein. | 0.466 |
| AEJ61832.1 | AEJ62406.1 | Spith_1571 | Spith_2151 | KEGG: hypothetical protein; SPTR: Putative uncharacterized protein. | PFAM: ABC transporter; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c21060 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein. | 0.466 |
| AEJ61832.1 | AEJ62407.1 | Spith_1571 | Spith_2152 | KEGG: hypothetical protein; SPTR: Putative uncharacterized protein. | ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sta:STHERM_c21070 transporter; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein. | 0.404 |
| AEJ61832.1 | AEJ62408.1 | Spith_1571 | Spith_2153 | KEGG: hypothetical protein; SPTR: Putative uncharacterized protein. | PFAM: Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: sta:STHERM_c21080 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein. | 0.576 |
| AEJ62406.1 | AEJ61832.1 | Spith_2151 | Spith_1571 | PFAM: ABC transporter; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c21060 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein. | KEGG: hypothetical protein; SPTR: Putative uncharacterized protein. | 0.466 |
| AEJ62406.1 | AEJ62407.1 | Spith_2151 | Spith_2152 | PFAM: ABC transporter; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c21060 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein. | ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sta:STHERM_c21070 transporter; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein. | 0.993 |
| AEJ62406.1 | AEJ62408.1 | Spith_2151 | Spith_2153 | PFAM: ABC transporter; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c21060 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein. | PFAM: Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: sta:STHERM_c21080 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein. | 0.992 |
| AEJ62406.1 | AEJ62409.1 | Spith_2151 | Spith_2154 | PFAM: ABC transporter; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c21060 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein. | PilT protein domain protein; PFAM: PIN domain; COGs: COG3744 conserved hypothetical protein; InterPro IPR002716; KEGG: sta:STHERM_c21090 hypothetical protein; PFAM: PilT protein, N-terminal; SPTR: PilT protein domain protein. | 0.442 |
| AEJ62406.1 | AEJ62410.1 | Spith_2151 | Spith_2155 | PFAM: ABC transporter; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c21060 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein. | KEGG: sta:STHERM_c21100 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.442 |
| AEJ62407.1 | AEJ60765.1 | Spith_2152 | Spith_0485 | ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sta:STHERM_c21070 transporter; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein. | Transcriptional regulator, CopG family; TIGRFAM: putative iron-only hydrogenase system regulator; KEGG: sta:STHERM_c18010 transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein. | 0.938 |
| AEJ62407.1 | AEJ61832.1 | Spith_2152 | Spith_1571 | ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sta:STHERM_c21070 transporter; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein. | KEGG: hypothetical protein; SPTR: Putative uncharacterized protein. | 0.404 |
| AEJ62407.1 | AEJ62406.1 | Spith_2152 | Spith_2151 | ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sta:STHERM_c21070 transporter; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein. | PFAM: ABC transporter; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c21060 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein. | 0.993 |
| AEJ62407.1 | AEJ62408.1 | Spith_2152 | Spith_2153 | ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sta:STHERM_c21070 transporter; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein. | PFAM: Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: sta:STHERM_c21080 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein. | 0.998 |
| AEJ62407.1 | AEJ62409.1 | Spith_2152 | Spith_2154 | ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sta:STHERM_c21070 transporter; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein. | PilT protein domain protein; PFAM: PIN domain; COGs: COG3744 conserved hypothetical protein; InterPro IPR002716; KEGG: sta:STHERM_c21090 hypothetical protein; PFAM: PilT protein, N-terminal; SPTR: PilT protein domain protein. | 0.586 |