Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62408.1PFAM: Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: sta:STHERM_c21080 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein. (295 aa)    
Predicted Functional Partners:
AEJ62407.1
ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sta:STHERM_c21070 transporter; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein.
 
 
 0.991
AEJ62406.1
PFAM: ABC transporter; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c21060 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
 
 0.984
AEJ60765.1
Transcriptional regulator, CopG family; TIGRFAM: putative iron-only hydrogenase system regulator; KEGG: sta:STHERM_c18010 transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein.
  
 
 0.853
AEJ62409.1
PilT protein domain protein; PFAM: PIN domain; COGs: COG3744 conserved hypothetical protein; InterPro IPR002716; KEGG: sta:STHERM_c21090 hypothetical protein; PFAM: PilT protein, N-terminal; SPTR: PilT protein domain protein.
       0.586
AEJ62410.1
KEGG: sta:STHERM_c21100 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.586
AEJ60486.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.522
AEJ60981.1
AAA ATPase; InterPro IPR003593; KEGG: sta:STHERM_c15210 hypothetical protein; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase.
    
 
 0.469
AEJ62411.1
Peptidase S1 and S6 chymotrypsin/Hap; PFAM: Trypsin; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254; KEGG: sta:STHERM_c21110 hypothetical protein; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SPTR: Peptidase S1 and S6 chymotrypsin/Hap.
     
 0.453
AEJ61934.1
uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...]
     
 0.449
AEJ62405.1
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
       0.441
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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