STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62421.1KEGG: sta:STHERM_c21200 hypothetical protein; SPTR: Putative uncharacterized protein. (281 aa)    
Predicted Functional Partners:
AEJ62422.1
PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: sta:STHERM_c21210 DNA helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase.
       0.799
rimO
Ribosomal protein S12 methylthiotransferase rimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
       0.797
AEJ62425.1
Transcriptional regulator, XRE family; COGs: COG1426 conserved hypothetical protein; KEGG: sta:STHERM_c21240 transcriptional regulator, XRE family; SPTR: Putative uncharacterized protein.
       0.786
AEJ62420.1
KEGG: sta:STHERM_c21190 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ62423.1
KEGG: sta:STHERM_c21220 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ62426.1
PFAM: Outer membrane lipoprotein carrier protein LolA; COGs: COG2834 Outer membrane lipoprotein-sorting protein; InterPro IPR004564; KEGG: sta:STHERM_c21250 hypothetical protein; PFAM: Outer membrane lipoprotein carrier protein LolA; SPTR: Outer membrane lipoprotein carrier protein LolA.
       0.726
AEJ61933.1
PFAM: Delta-aminolevulinic acid dehydratase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: sta:STHERM_c16130 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
  
 0.564
AEJ62427.1
PFAM: UvrB/uvrC motif; InterPro IPR001943; KEGG: sta:STHERM_c21260 hypothetical protein; PFAM: UvrB/UvrC protein; SPTR: UvrB/UvrC protein; manually curated.
       0.556
AEJ61934.1
uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...]
  
  
 0.463
AEJ62428.1
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
    0.430
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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