STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62422.1PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: sta:STHERM_c21210 DNA helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase. (683 aa)    
Predicted Functional Partners:
AEJ61639.1
PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: sta:STHERM_c07940 hypothetical protein; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase.
  
  
 
0.916
rimO
Ribosomal protein S12 methylthiotransferase rimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
  
  
 0.807
AEJ62421.1
KEGG: sta:STHERM_c21200 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.805
AEJ62425.1
Transcriptional regulator, XRE family; COGs: COG1426 conserved hypothetical protein; KEGG: sta:STHERM_c21240 transcriptional regulator, XRE family; SPTR: Putative uncharacterized protein.
       0.796
AEJ62420.1
KEGG: sta:STHERM_c21190 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ62423.1
KEGG: sta:STHERM_c21220 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ60289.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.765
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
 
 0.756
AEJ62426.1
PFAM: Outer membrane lipoprotein carrier protein LolA; COGs: COG2834 Outer membrane lipoprotein-sorting protein; InterPro IPR004564; KEGG: sta:STHERM_c21250 hypothetical protein; PFAM: Outer membrane lipoprotein carrier protein LolA; SPTR: Outer membrane lipoprotein carrier protein LolA.
       0.739
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
  
 0.713
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.