STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rimORibosomal protein S12 methylthiotransferase rimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (442 aa)    
Predicted Functional Partners:
AEJ62422.1
PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: sta:STHERM_c21210 DNA helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase.
  
    0.807
AEJ62421.1
KEGG: sta:STHERM_c21200 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.797
AEJ62425.1
Transcriptional regulator, XRE family; COGs: COG1426 conserved hypothetical protein; KEGG: sta:STHERM_c21240 transcriptional regulator, XRE family; SPTR: Putative uncharacterized protein.
       0.786
AEJ62420.1
KEGG: sta:STHERM_c21190 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ62423.1
KEGG: sta:STHERM_c21220 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ62426.1
PFAM: Outer membrane lipoprotein carrier protein LolA; COGs: COG2834 Outer membrane lipoprotein-sorting protein; InterPro IPR004564; KEGG: sta:STHERM_c21250 hypothetical protein; PFAM: Outer membrane lipoprotein carrier protein LolA; SPTR: Outer membrane lipoprotein carrier protein LolA.
       0.742
AEJ61634.1
PFAM: Radical SAM superfamily; TIGRFAM: 23S rRNA m2A2503 methyltransferase; COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR007197:IPR004383; KEGG: sta:STHERM_c08000 radical SAM enzyme, Cfr family; PFAM: Radical SAM; SPTR: Radical SAM enzyme, Cfr family; TIGRFAM: Ribosomal RNA large subunit methyltransferase RlmN.
 
  
 0.717
AEJ62427.1
PFAM: UvrB/uvrC motif; InterPro IPR001943; KEGG: sta:STHERM_c21260 hypothetical protein; PFAM: UvrB/UvrC protein; SPTR: UvrB/UvrC protein; manually curated.
       0.556
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
   0.502
AEJ62428.1
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.485
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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