STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62433.1PFAM: Amino acid permease; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COGs: COG0531 Amino acid transporter; InterPro IPR004841:IPR002178; KEGG: sta:STHERM_c21330 hypothetical protein; PFAM: Amino acid permease-associated region; Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Amino acid permease-associated region. (617 aa)    
Predicted Functional Partners:
AEJ62434.1
HAD superfamily (subfamily IA) hydrolase, TIGR02254; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; HAD superfamily (subfamily IA) hydrolase, TIGR02254; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR011951:IPR006402:IPR006439:IPR005834; KEGG: sta:STHERM_c21340 hypothetical protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD superfamily (Subfamily IA) hydrolase, TIGR [...]
       0.777
AEJ62436.1
Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain; GGDEF domain; COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001633; KEGG: sta:STHERM_c21360 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase/phosphodiesterase.
     
 0.647
AEJ62536.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: sta:STHERM_c22360 hypothetical protein; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN.
  
  
 0.642
dcd
Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
       0.634
AEJ62432.1
Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c21310 hypothetical protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
   
 
 0.576
AEJ62080.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611; KEGG: sta:STHERM_c17500 sugar kinase; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
  
  
 0.549
AEJ60307.1
PFAM: Alpha amylase, catalytic domain; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: sta:STHERM_c00200 hypothetical protein; PFAM: Glycosyl hydrolase, family 13, catalytic region; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha amylase catalytic region.
    
 0.523
AEJ60999.1
PFAM: Alpha amylase, catalytic domain; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: sta:STHERM_c15010 oligo-1,6-glucosidase; PFAM: Glycosyl hydrolase, family 13, catalytic region; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha amylase catalytic region.
    
 0.523
AEJ61152.1
Alpha amylase catalytic region; Catalyzes the reversible phosphorolysis of glucosylglycerate into alpha-D-glucose 1-phosphate (Glc1P) and D-glycerate. May be a regulator of intracellular levels of glucosylglycerate, a compatible solute that primarily protects organisms facing salt stress and very specific nutritional constraints. Cannot catalyze the phosphorolysis of sucrose.
    
 0.523
AEJ61918.1
PFAM: Alpha-amylase C-terminal beta-sheet domain; Alpha amylase, catalytic domain; COGs: COG0366 Glycosidase; InterPro IPR006589:IPR012850:IPR006047; KEGG: sta:STHERM_c15980 alpha-amylase type A isozyme precursor; PFAM: Glycosyl hydrolase, family 13, catalytic region; Alpha-amylase, C-terminal beta-sheet; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; Alpha-amylase, C-terminal beta-sheet; SPTR: Alpha amylase catalytic region.
    
 0.523
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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