Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62466.1PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c21640 hypothetical protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR. (425 aa)    
Predicted Functional Partners:
AEJ62467.1
PFAM: Outer membrane efflux protein; COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: sta:STHERM_c21650 hypothetical protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein.
 
   
 0.845
AEJ62468.1
TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: sta:STHERM_c21660 membrane fusion protein; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
     
 0.808
AEJ62470.1
KEGG: sta:STHERM_c21680 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.776
AEJ62469.1
Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: sta:STHERM_c21670 acriflavine resistance protein; PFAM: Acriflavin resistance protein; SPTR: Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
     
 0.768
AEJ62472.1
Hypothetical protein; PFAM: Putative lysophospholipase; COGs: COG2267 Lysophospholipase; KEGG: sta:STHERM_c21700 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.570
AEJ62465.1
MULE transposase, conserved domain-containing protein; Required for the transposition of the insertion element.
       0.542
AEJ62471.1
PFAM: Peptidase family U32; COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: sta:STHERM_c21690 hypothetical protein; PFAM: Peptidase U32; SPTR: Peptidase U32.
       0.494
AEJ62464.1
Integrase catalytic region; PFAM: Helix-turn-helix; Integrase core domain; InterPro IPR001584; KEGG: tde:TDE2472 ISTde1, transposase; PFAM: Integrase, catalytic core; SPTR: Integrase catalytic region.
       0.415
AEJ60715.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR001789:IPR001633:IPR 013767; KEGG: sta:STHERM_c04670 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclas [...]
  
  
 0.405
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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