STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62496.1PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein; InterPro IPR003489; KEGG: sta:STHERM_c21950 hypothetical protein; PFAM: Ribosomal protein S30Ae/sigma 54 modulation protein; SPTR: Ribosomal subunit interface protein; TIGRFAM: Ribosomal protein S30Ae/sigma 54 modulation protein. (104 aa)    
Predicted Functional Partners:
AEJ62495.1
RNA polymerase, sigma 54 subunit, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor; COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: sta:STHERM_c21940 RNA polymerase sigma-54 factor; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54; RNA polymerase sigma factor 54, core-binding; SPTR: RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigm [...]
 
  
 0.885
rpsU
PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; HAMAP: Ribosomal protein S21; InterPro IPR001911; KEGG: sta:STHERM_c06550 30S ribosomal protein S21; PFAM: Ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
 
 
 
 0.858
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
     
 0.832
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
   
 0.813
rpmA
PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; COGs: COG0211 Ribosomal protein L27; HAMAP: Ribosomal protein L27; InterPro IPR001684; KEGG: sta:STHERM_c10280 50S ribosomal protein L27; PFAM: Ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.797
AEJ62498.1
Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein.
  
  
 0.797
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
   0.795
rpsI
PFAM: Ribosomal protein S9/S16; COGs: COG0103 Ribosomal protein S9; InterPro IPR000754; KEGG: sta:STHERM_c21160 30S ribosomal protein S9; PFAM: Ribosomal protein S9; SPTR: 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.794
rpmH
PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; HAMAP: 50S ribosomal protein L34; InterPro IPR000271; KEGG: sta:STHERM_c00060 50S ribosomal protein L34; PFAM: Ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: Ribosomal protein L34.
   
 
 0.793
rpmC
PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; InterPro IPR001854; KEGG: sta:STHERM_c05040 50S ribosomal protein L29; PFAM: Ribosomal protein L29; SPTR: LSU ribosomal protein L29P; TIGRFAM: Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
    
 
 0.788
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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