Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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AEJ62510.1PFAM: Peptidase family M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: sta:STHERM_c22090 hypothetical protein; PFAM: Peptidase M23; SPTR: Peptidase M23. (405 aa)    
Predicted Functional Partners:
AEJ62509.1
PFAM: Bacterial capsule synthesis protein PGA_cap; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: sta:STHERM_c22100 hypothetical protein; PFAM: Capsule synthesis protein, CapA; SPTR: Capsule synthesis protein, CapA.
       0.579
AEJ61223.1
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
   
   0.560
thyX
Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
       0.504
AEJ62507.1
PFAM: Phosphoglycerate mutase family; COGs: COG2062 Phosphohistidine phosphatase SixA; InterPro IPR013078; KEGG: sta:STHERM_c22070 hypothetical protein; PFAM: Phosphoglycerate mutase; SPTR: Putative uncharacterized protein; manually curated.
       0.493
AEJ61705.1
Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR011816; KEGG: sta:STHERM_c07150 penicillin-binding protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A.
  
   
 0.437
AEJ61917.1
Glycoside hydrolase family 13 domain protein; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); InterPro IPR004193; KEGG: sta:STHERM_c15960 hypothetical protein; PFAM: Glycoside hydrolase, family 13, N-terminal; SPTR: Glycoside hydrolase family 13 domain protein.
 
   
 0.410
AEJ61308.1
PFAM: Peptidase family M23; LysM domain; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: sta:STHERM_c10110 LysM domain/M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidase M23.
 
   
 0.403
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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