Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEJ62530.1ATP-binding region ATPase domain protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; InterPro IPR003594; KEGG: sta:STHERM_c22300 hypothetical protein; PFAM: ATP-binding region, ATPase-like; SPTR: ATP-binding region ATPase domain protein. (193 aa)    
Predicted Functional Partners:
AEJ62529.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: sta:STHERM_c22290 anti sigma B factor antagonist RsbV; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
  
 
 0.952
AEJ62528.1
Protein serine/threonine phosphatase with GAF(s) sensor(s); PFAM: GAF domain; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003018:IPR010822:IPR001932; KEGG: sta:STHERM_c22280 sigma factor SigB regulation protein; PFAM: Sporulation stage II, protein E C-terminal; GAF; SMART: Protein phosphatase 2C-related; GAF; SPTR: Protein serine phosphatase with GAF(S) sensor(S).
  
 
 0.887
AEJ60492.1
Multi-sensor hybrid histidine kinase; PFAM: 7TM diverse intracellular signalling; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: sta:STHERM_c02220 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, p [...]
  
  
 0.875
AEJ61090.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013656:IPR003661:IPR003594:IPR 001789:IPR008207; KEGG: sta:STHERM_c14170 two-component system, sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; Signal transduction response regulator, receiver region; Signal transducti [...]
  
  
 0.875
AEJ60715.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR001789:IPR001633:IPR 013767; KEGG: sta:STHERM_c04670 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclas [...]
  
 
 0.852
AEJ61206.1
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.843
AEJ61214.1
KEGG: sta:STHERM_c09150 hypothetical protein; SPTR: Putative uncharacterized protein.
   
    0.843
AEJ61219.1
PFAM: MotA/TolQ/ExbB proton channel family; COGs: COG1291 Flagellar motor component; InterPro IPR002898; KEGG: sta:STHERM_c09200 chemotaxis protein MotA; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel.
   
    0.843
AEJ61668.1
Flagellar hook-associated protein FlgK; PFAM: Flagellin hook IN motif; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK; COGs: COG1256 Flagellar hook-associated protein; InterPro IPR010810:IPR010930:IPR002371; KEGG: sta:STHERM_c07620 flagellar hook-associated protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK.
   
    0.843
AEJ61734.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645:IPR003658; KEGG: sta:STHERM_c06750 anti-anti-sigma factor; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
  
 
 0.841
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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