STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ62531.1KEGG: sta:STHERM_c22310 hypothetical protein; SPTR: Putative uncharacterized protein. (387 aa)    
Predicted Functional Partners:
AEJ62530.1
ATP-binding region ATPase domain protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; InterPro IPR003594; KEGG: sta:STHERM_c22300 hypothetical protein; PFAM: ATP-binding region, ATPase-like; SPTR: ATP-binding region ATPase domain protein.
       0.763
AEJ62529.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: sta:STHERM_c22290 anti sigma B factor antagonist RsbV; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
       0.705
AEJ62528.1
Protein serine/threonine phosphatase with GAF(s) sensor(s); PFAM: GAF domain; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003018:IPR010822:IPR001932; KEGG: sta:STHERM_c22280 sigma factor SigB regulation protein; PFAM: Sporulation stage II, protein E C-terminal; GAF; SMART: Protein phosphatase 2C-related; GAF; SPTR: Protein serine phosphatase with GAF(S) sensor(S).
       0.588
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.